Thiabendazole Cas: 148-79-8
| Nọmba katalogi | XD92377 |
| Orukọ ọja | Thiabendazole |
| CAS | 148-79-8 |
| Molecular Formula | C10H7N3S |
| Òṣuwọn Molikula | 201.25 |
| Awọn alaye ipamọ | Ibaramu |
| Ti irẹpọ Owo idiyele koodu | 29414000 |
Ọja Specification
| Ifarahan | funfun gara lulú |
| Asay | 99% iṣẹju |
| Ojuami Iyo | 296-303°C |
| Omi | <0.5% |
Thiabendazole jẹ itọsẹ benzimidazole ti a ṣe afihan bi oogun ti ogbo lakoko awọn ọdun 1960 ati nigbamii bi oogun anthelminthic eniyan.O ni iṣẹ ṣiṣe anthelminthic ti o gbooro ti o munadoko ti o munadoko lodi si awọn oriṣi ti awọn akoran nematode.O jẹ mejeeji ovicidal ati larvicidal.O tun munadoko pupọ si ọpọlọpọ awọn saprophytic ati awọn elu pathogenic in vitro ati pe o tun ṣe afihan egboogi-iredodo, antipyretic ati awọn ohun-ini analgesic ninu awọn ẹranko yàrá[1].Ni ile-iwosan, o jẹ lilo akọkọ lodi si Strongyloides stercoralis ati awọn aṣikiri larva ti awọ.
Ilana ti iṣe ko ni oye kedere.O ti ṣe afihan lati ṣe idiwọ mitochondrial fumurate reductase, eyiti o jẹ pato fun awọn helminths[2].Thiabendazole tun le ni ipa lori awọn microtubules parasite, nipasẹ ọna ti o jọra si eyiti a ṣe apejuwe fun mebendazole (wo Mebendazole).
