Spectinomycin dihydrochloride pentahydrate CAS: 22189-32-8 Funfun crystaline lulú
| Nọmba katalogi | XD90369 |
| Orukọ ọja | Spectinomicin dihydrochloride pentahydrate |
| CAS | 22189-32-8 |
| Ilana molikula | C14H24N2O7 · 2HCl · 5H2O |
| Òṣuwọn Molikula | 495.30 |
| Awọn alaye ipamọ | 2 si 8 °C |
| Ti irẹpọ Owo idiyele koodu | 29419090 |
Ọja Specification
| Ayẹwo | 99% |
| Ifarahan | Kirisitaini funfun lulú |
Lati ṣe iwadii awọn ajakale-ara molikula ti awọn ipinya ti Neisseria gonorrhoeae lati Saskatchewan, Canada, ni lilo Neisseria gonorrhoeae multi antigen type typing (NG-MAST), ati lati ṣe ayẹwo awọn ẹgbẹ laarin ifaragba antimicrobial (AMS) ati awọn oriṣi igara pato (STs) 320 lẹẹkọọkan. , ti a gba laarin 2003 ati 2008, ti tẹ nipasẹ NG-MAST.A ṣe akojọpọ awọn ST ti ọkan ninu awọn alleles wọn wọpọ ati ekeji yatọ nipasẹ ≤1% ni ọna DNA.AMS ti pinnu nipasẹ dilution agar (CLSI) si awọn egboogi meje.N gonorrheae isolates ni a pinnu si 82 olukuluku NG-MAST STs ati awọn ẹgbẹ 18 NG-MAST ST pẹlu awọn ẹgbẹ 25, 3655, 921, 3654, 3657 ati 3656 ti o ni ninu% 513.1. / 320) ti awọn ipinya.Awọn ipinya gonorrheae ti o ni ifaragba si gbogbo awọn ajẹsara ti idanwo jẹ pataki (p<0.05) ni nkan ṣe pẹlu ST 25 (87%).Awọn ẹgbẹ pataki miiran laarin ST ati AMS pẹlu: ST 3654 ati awọn iyasọtọ pẹlu awọn ifọkansi inhibitory ti o kere ju ti ≥0.03 mg/L si iran kẹta ceph alosporins;ST 3711 (100%) ati TRNG;ati ST/ẹgbẹ 3654 (43%) ati chromosomal resistance si penicillin ati tetracycline.Orisirisi awọn NG-MAST STs/awọn ẹgbẹ ni pataki ni nkan ṣe pẹlu awọn ipinya pẹlu resistance chromosomal si tetracycline.Awọn iyasọtọ ti o lodi si ciprofloxacin (n=5) ati azithromycin (n=2) farahan bi STs kọọkan.Awọn ẹgbẹ pataki ni a ṣe akiyesi laarin awọn STs kọọkan, ibalopo ati ọjọ ori ti alaisan, ati awọn pinpin agbegbe ati akoko.Nitoripe awọn ST ni awọn orilẹ-ede oriṣiriṣi yatọ, lilo NG-MAST fun asọtẹlẹ AMS ni agbaye nilo ikẹkọ siwaju sii.
