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Awọn ọja

Methyl 4- (4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-carboxylate (Z6) CAS: 289042-11-1

Apejuwe kukuru:

Nọmba Katalogi: XD93411
Cas: 289042-11-1
Fọọmu Molecular: C17H20FN3O4S
Ìwúwo Molikula: 381.42
Wiwa: O wa
Iye:  
Iṣakojọpọ:  
Apo Ọpọ: Beere Quote

 


Alaye ọja

ọja Tags

Nọmba katalogi XD93411
Orukọ ọja Methyl 4- (4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-carboxylate (Z6)
CAS 289042-11-1
Fọọmu Molecularla C17H20FN3O4S
Òṣuwọn Molikula 381.42
Awọn alaye ipamọ Ibaramu

Ọja Specification

Ifarahan funfun lulú
Asay 99% iṣẹju

 

Methyl 4- (4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-carboxylate, ti a tun mọ ni Z6, jẹ agbopọ pẹlu awọn ohun elo ti o pọju ni aaye ti awọn oogun oogun. .Iwaju ẹgbẹ phenyl ti o rọpo fluoro ti o somọ oruka pyrimidine ni imọran pe Z6 le ṣe ajọṣepọ pẹlu awọn ibi-afẹde ti ibi, ti o jẹ ki o jẹ oludije ti o ni ileri fun awọn igbiyanju iṣawari oògùn.Iṣakojọpọ ti ẹgbẹ isopropyl ṣe alekun hydrophobicity ti agbo, ti o ni ilọsiwaju agbara rẹ lati wọ inu awọn membran ti ibi ati de ibi ibi-afẹde ti a pinnu. Abala pataki miiran ti Z6 ni wiwa ti ẹgbẹ amino acid N-methyl-N-methylsulfonyl.Ẹgbẹ iṣẹ ṣiṣe yii ti ni nkan ṣe pẹlu imudara iduroṣinṣin ti iṣelọpọ ti yellow ati idinku awọn ipa ibi-afẹde ti o pọju.O tun le ṣe alabapin si solubility agbo ni awọn agbegbe pola.Awọn ohun-ini wọnyi le jẹ niyelori ni idagbasoke awọn agbo ogun bioactive.Iwaju ti ẹgbẹ methyl ester ni Z6 pese iwọn ti iduroṣinṣin ati irọrun ti mimu.Ni afikun, ẹgbẹ carboxylate ni ipo 5 ti iwọn pyrimidine le jẹ aaye ti o pọju fun awọn iyipada kemikali, gbigba fun awọn iwadii ibatan iṣẹ-ṣiṣe ati iṣapeye ti awọn ohun-ini oogun. eroja (API) fun itọju orisirisi awọn arun.O le ṣawari fun agbara rẹ bi oluranlowo egboogi-iredodo, oogun aarun ayọkẹlẹ, tabi ni awọn itọju akàn.Apapọ alailẹgbẹ ti awọn ẹgbẹ iṣẹ-ṣiṣe le pese awọn aye fun awọn ibaraenisepo ti ibi ti o yan, ti o jẹ ki o jẹ oludije ti o wuyi fun modulation ibi-afẹde oogun.Pẹlupẹlu, eka igbekale Z6 ati oniruuru jẹ ki o jẹ aaye ibẹrẹ ti o nifẹ fun idagbasoke awọn ile-ikawe moleku kekere tabi awọn scaffolds kemikali.O le ṣe bi ohun amorindun fun iṣelọpọ ti awọn itọsẹ ti o yatọ, ti o jẹ ki iṣawari ti awọn ibatan iṣẹ-ṣiṣe ati idanimọ awọn agbo ogun fun iṣapeye siwaju sii. orisirisi elegbogi ohun elo.Agbara rẹ bi API, papọ pẹlu iṣipopada lati ṣe atunṣe ati iṣapeye, jẹ ki o jẹ agbo-ara moriwu fun iṣawari oogun ati awọn akitiyan idagbasoke.Awọn iwadii siwaju ati iwadii jẹ pataki lati ṣawari ni kikun ati ijanu agbara itọju ailera rẹ.


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    Methyl 4- (4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-carboxylate (Z6) CAS: 289042-11-1