Doxycycline hyclate CAS: 24390-14-5 99% Yellow crystalline lulú
| Nọmba katalogi | XD90368 |
| Orukọ ọja | Doxycycline hyclate |
| CAS | 24390-14-5 |
| Ilana molikula | C22H24N2O8·HCl·0.5C2H6O·0.5H2O |
| Òṣuwọn Molikula | 512.94 |
| Awọn alaye ipamọ | 2 si 8 °C |
| Ti irẹpọ Owo idiyele koodu | 29413000 |
Ọja Specification
| Aimọ́ A | <2% |
| AimọB | <2% |
| Yiyi pato | -105 to -120 |
| pH | 2-3 |
| Iwa aimọ C | <0.5% |
| AimọD | <0.5% |
| Isonu lori Gbigbe | 1.4-2.8% |
| Ayẹwo | 99% |
| Aloku lori Iginisonu | <0.4% |
| Absorbility | 300-335 |
| Eyikeyi miiran nikan aimọ | <0.5% |
| Ifarahan | Yellow crystalline lulú |
| Àìmọ́ F | <0.5% |
| AimọE | <0.5% |
| Ethyl Ọtí | 4.5 - 6% |
| Absorbency ti aimọ | <0.07% |
Ipilẹṣẹ biofilm lori abutment ehín le ja si peri-implant mucositis ati peri-implantitis ti o tẹle.Awọn ọran wọnyi ni itọju ile-iwosan pẹlu awọn oogun apakokoro bii doxycycline (Doxy).Nibi a lo ọna elekitiroki kan ti polarization cathodic lati wọ Doxy si oju ita ti ohun elo abutment ehín.Ilẹ ti a bo Doxy ṣe afihan itusilẹ ti nwaye ni iyo fosifeti-buffered lakoko wakati 24 akọkọ.Bibẹẹkọ, iye pataki ti Doxy wa lori dada fun o kere ju awọn ọsẹ 2 paapaa lori apẹẹrẹ 5 mA-3 h pẹlu iye Doxy ti o ga julọ, ni iyanju mejeeji ibẹrẹ ati agbara bacteriostatic igba pipẹ ti dada ti a bo.Kemistri oju-aye ni a ṣe atupale nipasẹ x-ray photoelectron spectroscopy ati spectrometry ibi-iwọn keji.A ṣe agbeyẹwo oju-aye lori oju-aye nipasẹ wiwo itujade aaye airi microscopy ati profilometry-ina buluu.Akoko polarization gigun lati wakati 1 si 5 ati iwuwo lọwọlọwọ giga lati 1 si 15 mA cm(-2) yorisi iye Doxy ti o ga julọ lori surfa ce.Ilẹ ti bo nipasẹ Layer ti Doxy ti o kere ju 100 nm laisi awọn ayipada pataki ni oju-aye oju-aye.Ohun-ini antibacterial ti oju ti a bo Doxy ni a ṣe atupale nipasẹ biofilm ati awọn igbelewọn idagba planktonic nipa lilo Staphylococcus epidermidis.Awọn ayẹwo ti a bo doxy dinku ikojọpọ biofilm mejeeji ati idagbasoke planktonic ninu aṣa broth, ati pe o tun ṣe idiwọ idagbasoke kokoro-arun lori awọn awo agar.Ipa antibacterial ni okun sii fun awọn ayẹwo ti 5 mA-3 h ti a bo pẹlu iye ti o ga julọ ti Doxy ni akawe si ti 1 mA-1 h.Gegebi bi, ohun abutment dada ti a bo pẹlu Doxy ni o ni agbara fun idilọwọ awọn ileto kokoro arun nigba ti o ba farahan si ẹnu iho.Doxy-coating le jẹ ọna ti o le yanju lati ṣakoso peri-implant mucositis ati idilọwọ lilọsiwaju rẹ sinu peri-implantitis.
