Urease CAS: 9002-13-5
| Nọmba katalogi | XD90388 |
| Orukọ ọja | Urease |
| CAS | 9002-13-5 |
| Ilana molikula | N/A |
| Òṣuwọn Molikula | - |
| Awọn alaye ipamọ | 2 si 8 °C |
| Ti irẹpọ Owo idiyele koodu | 35079090 |
Ọja Specification
| Ayẹwo | 99% |
| Ifarahan | funfun lulú |
Nickel jẹ ipinnu aarun ayọkẹlẹ fun pathogen inu eniyan Helicobacter pylori.Nitootọ, H. pylori ni awọn enzymu nickel-meji ti o ṣe pataki fun imunisin vivo, [NiFe] hydrogenase ati urease, ifosiwewe virulence lọpọlọpọ ti o ni awọn ions nickel 24 fun eka ti nṣiṣe lọwọ.Nitori awọn enzymu meji wọnyi, iwalaaye H. pylori gbarale ipese pataki ti nickel, ti o tumọ si iṣakoso to muna ti pinpin ati ibi ipamọ rẹ.Ninu atunyẹwo yii, a yoo ṣafihan awọn ipa ọna ti imuṣiṣẹ ti awọn enzymu nickel gẹgẹbi awọn ilana atilẹba ti a rii ni H. pylori fun gbigbe, gbigbe kakiri ati pinpin nickel laarin awọn enzymu meji.Iwọnyi pẹlu (i) eto gbigba nickel ti ita-membrane, olutọpa ti o gbẹkẹle FrpB4 TonB, (ii) awọn eka amuaradagba agbekọja ati awọn nẹtiwọọki ibaraenisepo ti o ni ipa ninu gbigbe kakiri nickel ati pinpin laarin urease ati hydrogenase ati, (iii) Helicobacter kan pato awọn ọlọjẹ nickel-abuda ti o ni ipa ninu ibi ipamọ nickel ati pe o le ṣe ipa ti metallo-chaperones.Nikẹhin, a yoo jiroro lori ipa ti awọn alabaṣiṣẹpọ gbigbe kakiri nickel ni virulence ati daba wọn bi awọn ibi-afẹde itọju aramada fun awọn itọju lodi si ikolu H. pylori.
