Tazobactam Cas: 89786-04-9
| Nọmba katalogi | XD92373 |
| Orukọ ọja | Tazobactam |
| CAS | 89786-04-9 |
| Molecular Formula | C10H12N4O5S |
| Òṣuwọn Molikula | 300.29 |
| Awọn alaye ipamọ | -15 si -20 °C |
| Ti irẹpọ Owo idiyele koodu | 29419000 |
Ọja Specification
| Ifarahan | Funfun si pa-funfun lulú |
| Asay | 99% iṣẹju |
| Omi | <0.5% |
| Yiyi pato | +127 to +139 |
| Awọn irin ti o wuwo | <20ppm |
| Aloku lori Iginisonu | <0.1% |
| Lapapọ Awọn Aimọ | <1.0% |
Tazobactam jẹ penicillanic acid sulfone ti o jẹ iru ẹkọ si sulbactam.O jẹ β-lactamaseinhibitor ti o lagbara diẹ sii ju sulbactam ati pe o ni iṣẹ-iwoye ti o gbooro diẹ sii ju clavulanic acid.O ni ipakokoro alailagbara pupọ.Tazobactam wa ni iwọn lilo ti o wa titi, awọn akojọpọ injectable pẹlu piperacillin, penicillin ti o gbooro pupọ ti o ni ibamu pẹlu ipin 8: 1 ti piperacillin sodium si tazobactamsodium nipasẹ iwuwo ati tita labẹ orukọ iṣowo Zosyn. Awọn oogun elegbogi ti awọn oogun meji naa jọra pupọ.Mejeeji ni awọn igbesi aye idaji kukuru (t1/2 ~ 1 wakati), jẹ amuaradagba diẹ, ni iriri iṣelọpọ kekere, ati pe wọn yọ awọn fọọmu aiṣiṣẹ jade ninu ito ni awọn ifọkansi giga.
Awọn itọkasi ti a fọwọsi fun piperacillin-tazobactamcombination pẹlu itọju appendicitis, postpartumendometritis, ati arun iredodo pelvic ti o fa nipasẹβ-lactamase-producing E. coli ati Bacteroides spp., awọn akoran igbekalẹ awọ ara ati awọ ti o fa nipasẹ β-lactamase–producingS.aureus, ati pneumonia ti o ṣẹlẹ nipasẹ β-lactamase-producingstrains ti H. influenzae.
