Platinum(IV) chloride Cas: 13454-96-1 Pupa-brown Powder
Nọmba katalogi | XD90688 |
Orukọ ọja | Platinum (IV) kiloraidi |
CAS | 13454-96-1 |
Ilana molikula | Cl4Pt |
Òṣuwọn Molikula | 336.89 |
Awọn alaye ipamọ | Fipamọ ni isalẹ + 30 ° C |
Ti irẹpọ Owo idiyele koodu | 28439090 |
Ọja Specification
Ifarahan | Pupa-brown Powder |
Ayẹwo | 99% |
Dìkanra | 4.303 |
Ojuami yo | 370℃ |
logP | 2.75550 |
Lati ṣe agbero oogun ati pekito jiini PEG-PEI-Pt.Polyethyleneglycol (PEG) ni a so pọ mọ polyethylenimine (PEI 600) ati platinum tetrachloride;PEG-PEI-Pt eka ti a ṣẹda ni ethanol.Eka naa jẹ afihan nipasẹ XRD, UV-VIS ati FT-IR ati pe a ṣe idanwo ifunmọ DNA nipasẹ idanwo iyipada gbigbe elekitirophoretic.A ṣe ayẹwo ṣiṣeeṣe sẹẹli nipasẹ MTT assay ni awọn sẹẹli Hela, B16, A293 ati COS-7 ati ṣiṣe gbigbe in vitro ni a ṣe iwọn ni awọn sẹẹli A293 ati B16. Ilana ti PEG-PEI-Pt ni a ṣe afihan nipasẹ XRD, UV-VIS ati FT. -IR.PEG-PEI-Pt eka ni anfani lati di DNA ni ipin iwuwo N/P ti 0.4: 1;eka naa fihan cytotoxicity lori awọn sẹẹli Hela ati B16.Ẹka naa ni ṣiṣe gbigbe ti o ga julọ ni awọn sẹẹli A293 ati B16 ju PEI 600. Olumu oogun aramada kan ati pikito jiini PEG-PEI-Pt ni a ṣe ni aṣeyọri.