o-Cresolphthalein Complexone CAS: 2411-89-4 White lulú
| Nọmba katalogi | XD90463 |
| Orukọ ọja | o-Cresolphthalein Complexone |
| CAS | 2411-89-4 |
| Ilana molikula | C32H32N2O12 |
| Òṣuwọn Molikula | 636.62 |
| Awọn alaye ipamọ | Ibaramu |
| Ti irẹpọ Owo idiyele koodu | 2932209090 |
Ọja Specification
| Isonu lori Gbigbe | 7.23% |
| Ifarahan | funfun lulú |
| Ayẹwo | 99% |
| Ibi ipamọ otutu | + 20 ° C |
| Òṣuwọn Molikula | 636.6 |
| Solubility | Ko o eleyi ti ojutu |
| Aloku lori Iginisonu | 0.5% ti o pọju |
| Nitrojiini | 4.1-4.7% |
| Lambda max | 573nm ni 0.1N soda hydroxide |
| Lama Max | 575(377)nm ninu 0.1 N soda hydroxide |
| Erogba | 58-63% |
Awọn ọlọjẹ morphogenetic egungun (BMPs) ṣe ipa pataki ninu dida egungun ati kerekere.Fun awọn ohun-ini wọnyi, awọn BMP ti wa ni iṣẹ ni aaye ti imọ-ẹrọ ti ara lati fa isọdọtun egungun ninu awọn tisọ ti o bajẹ.Lati bori awọn ilọkuro nitori lilo gbogbo awọn ọlọjẹ, awọn peptides sintetiki ti o wa lati ọdọ BMP obi wọn ti jade bi awọn ohun elo ti o ni ileri fun apẹrẹ biomaterial.Lori ilẹ igbekale ti awọn ile-iṣẹ olugba BMP-2 esiperimenta ti a royin ninu awọn iwe-iwe, a ṣe apẹrẹ awọn peptides mẹta, ti n ṣe atunṣe agbegbe BMP-2 ti o ni iduro fun isopọmọ si iru olugba II, ActRIIB.Awọn peptides wọnyi jẹ afihan nipasẹ NMR, ati awọn ẹya igbekale ti wiwo abuda peptide-receptor ni afihan nipasẹ awọn adanwo docking.Affinities abuda Peptide-receptor ni a ṣe atupale nipasẹ ọna ELISA ati awọn ilana imupadabọ pilasima dada.Pẹlupẹlu, awọn idanwo cellular ni a ṣe lati ṣe ayẹwo awọn ohun-ini osteoinductive wọn.A chimera peptide, ti o gba nipa apapọ awọn ions ibudo ọkọọkan 73-92 ati 30-34 ti BMP-2, ṣe afihan isunmọ ti o dara julọ fun ActRIIB ninu jara ati pe o jẹ aṣoju ibẹrẹ ti o dara fun apẹrẹ ti awọn agbo ogun tuntun ti o le ṣe ẹda awọn ohun-ini osteogenic ti obi BMP-2.
