L-Cystin CAS: 56-89-3 99% Awọn kirisita funfun tabi lulú kirisita
| Nọmba katalogi | XD90322 |
| Orukọ ọja | L-Cystine |
| CAS | 56-89-3 |
| Ilana molikula | C6H12N2O4S2 |
| Òṣuwọn Molikula | 240.30 |
| Awọn alaye ipamọ | Ibaramu |
| Ti irẹpọ Owo idiyele koodu | 29309013 |
Ọja Specification
| Ifarahan | Awọn kirisita funfun tabi lulú kirisita |
| Ayẹwo | 99% |
| Ipele | USP32 |
| Yiyi pato | -215° si -225° |
| Awọn irin ti o wuwo | <0.0015% |
| AS | ti o pọju 1.5ppm |
| SO4 | ti o pọju 0.040%. |
| Fe | <0.003% |
| Isonu lori Gbigbe | 0.20% ti o pọju |
| Aloku lori Iginisonu | 0.10% ti o pọju |
| Cl | 0.10% ti o pọju |
Awọn ẹya gara ti awọn ile-iṣẹ carboxypeptidase T (CpT) pẹlu phenylalanine ati awọn analogs sobusitireti arginine - benzylsuccinic acid ati (2-guanidinoethylmercapto) succinic acid - ni ipinnu nipasẹ ọna rirọpo molikula ni awọn ipinnu ti 1.57 Å ati 1.62 Å lati ṣe alaye profaili pataki sobusitireti. ti enzymu.Leu211 Konsafetifu ati awọn iṣẹku Leu254 (tun wa ninu mejeeji carboxypeptidase A ati carboxypeptidase B) ni a fihan lati jẹ awọn ipinnu igbekalẹ fun idanimọ ti awọn sobusitireti hydrophobic, lakoko ti Asp263 jẹ fun idanimọ awọn sobusitireti ti o ni idiyele daadaa.Awọn iyipada ti awọn ipinnu ipinnu wọnyi ṣe atunṣe profaili sobusitireti: iyatọ CpT Leu211Gln gba awọn ohun-ini carboxypeptidase B, ati iyatọ CpT Asp263Asn carboxypeptidase A-like selectivity.Loop Pro248-Asp258 ti o n ba Leu254 ati Tyr255 han pe o ni iduro fun idanimọ iyokù C-terminal ti sobusitireti.Isopọ sobusitireti ni aaye S1' yori si iyipada ligand-dep endent ti lupu yii, ati iṣipopada ẹwọn ẹgbẹ Leu254 ṣe agbekalẹ atunto conformation ti aloku Glu277 pataki fun catalysis.Eyi jẹ oye aramada sinu yiyan sobusitireti ti metallocarboxypeptidase ti o ṣe afihan pataki awọn ibaraenisepo laarin aaye S1 'ati ile-iṣẹ katalitiki.
