D-Glutamic acid CAS: 6893-26-1 99% funfun lulú
Nọmba katalogi | XD90313 |
Orukọ ọja | D-Glutamic acid |
CAS | 6893-26-1 |
Ilana molikula | C5H9NO4 |
Òṣuwọn Molikula | 147.13 |
Awọn alaye ipamọ | Ibaramu |
Ti irẹpọ Owo idiyele koodu | 29224200 |
Ọja Specification
Ifarahan | Funfun okuta lulú |
Ayẹwo | 99% |
Yiyi pato | -31 si -32.2 |
Awọn irin ti o wuwo | <10ppm |
AS | <1ppm |
pH | 3 - 3.5 |
SO4 | <0.020% |
Fe | <10ppm |
Isonu lori Gbigbe | <0.20% |
Aloku lori Iginisonu | <0.10% |
NH4 | <0.02% |
Cl | <0.02% |
Ipinle ti Solusan | > 98% |
γ-Glutamyltranspeptidases (γ-GTs) di γ-glutamyl amide mnu ti glutathione ati gbe ẹgbẹ γ-glutamyl ti a tu silẹ si omi (hydrolysis) tabi awọn amino acids (transpeptidation) ti o gba silẹ.Awọn enzymu ti o wa ni ibi gbogbo ṣe ipa pataki ninu biosynthesis ati ibajẹ ti glutathione, ati ni detoxification xenobiotic.Nibi ti a jabo 3Å o ga gara be ti Bacillus licheniformis γ-GT (BlGT) ati awọn ti o ti eka rẹ pẹlu l-Glu.Awọn ẹya X-ray jẹrisi pe BlGT jẹ ti idile superfamily N-terminal nucleophilic hydrolase ati ṣafihan pe amuaradagba ni aaye ti o ṣi silẹ ti nṣiṣe lọwọ bii eyiti o royin fun enzymu isokan lati Bacillus subtilis, ṣugbọn yatọ si awọn ti a ṣe akiyesi fun eniyan γ-GT ati fun γ-GT lati awọn microorganisms miiran.Awọn data daba pe abuda ti l-Glu nfa atunṣeto iru C-terminal ti BlGT ipin nla ati gba idanimọ ti iṣupọ ti awọn iṣẹku acid ti o ni ipa ninu idanimọ ion irin kan.T ipa ti awọn wọnyi iṣẹku lori conformational iduroṣinṣin ti BlGT ti a ti iwadi nipa characterizing awọn autoprocessing, enzymatic aṣayan iṣẹ-ṣiṣe, kemikali ati ki o gbona denaturation ti mẹrin titun Ala nikan mutanti.Awọn abajade fihan pe rirọpo Asp568 pẹlu Ala kan ni ipa lori iṣelọpọ adaṣe mejeeji ati iduroṣinṣin igbekalẹ ti amuaradagba.