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Awọn ọja

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine iyọ Cas:6578-06-9 99% Funfun si ina brown lulú

Apejuwe kukuru:

Nọmba Katalogi: XD90137
Cas: 6578-06-9
Fọọmu Molecular: C8H5BrClNO4P·C7H10N
Ìwọ̀n Molikula: 433.62
Wiwa: O wa
Iye:  
Iṣakojọpọ: 5g20 USD
Apo Ọpọ: Beere Quote

 

 

 

 

 

 

 


Alaye ọja

ọja Tags

Nọmba katalogi XD90137
Orukọ ọja BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine iyọ.
CAS 6578-06-9
Ilana molikula C8H5BrClNO4P·C7H10N
Òṣuwọn Molikula 433.62
Awọn alaye ipamọ -15 si -20 °C
Ti irẹpọ Owo idiyele koodu 29339980

 

Ọja Specification

Ifarahan Funfun / ina brown lulú
Asay ≥ 99%
Ojuami yo 194-195ºC
Oju omi farabale 580.2°C ni 760 mmHg
oju filaṣi 304.7°C
Solubility DMF: 20 mg/ml
Solubility tiotuka ni dimethylformamide, insoluble ninu omi.
Ifamọ Ni imọlara si ina, ifarabalẹ si afẹfẹ, ati ifarabalẹ si ooru

 

Iṣẹ ṣiṣe ti ara: BCIP (iyọ BCIP p-toluidine; iyọ X-phosphate p-toluidine) jẹ sobusitireti chromogenic fun wiwa awọ-ara ti iṣẹ ṣiṣe phosphatase ipilẹ.

Awọn majele Shiga (Stxs) jẹ iṣelọpọ nipasẹ enterohemorrhagic Escherichia coli (EHEC), eyiti o fa awọn akoran eniyan pẹlu abajade apaniyan nigbagbogbo.Awọn laini sẹẹli Vero, ti o jade lati kidinrin obo alawọ ewe Afirika, ṣe aṣoju boṣewa goolu fun ṣiṣe ipinnu awọn ipa cytotoxic ti Stxs.Pelu lilo agbaye wọn, imọ nipa awọn ẹya gangan ti Stx receptor glycosphingolipids (GSLs) ati apejọ wọn ni awọn rafts ọra ko dara.Nibi a ṣe afihan igbekale igbekalẹ igbekalẹ ti awọn GSL olugba Stx ati pinpin wọn si awọn membran-sooro detergent (DRMs), eyiti a pese sile lati awọn sẹẹli Vero-B4 ati lo bi awọn deede raft ọra.A ṣe idanimọ globotriaosylceramide (Gb3Cer) ati globotetraosylceramide (Gb4Cer) gẹgẹbi awọn olugba GSL fun Stx1a, Stx2a, ati Stx2e subtypes nipa lilo wiwa apọju TLC ni idapo pẹlu MS.Olugba Stx ti ko wọpọ, globopentaosylceramide (Gb5Cer, Galβ3GalNAcβ3Galα4Galβ4Glcβ1Cer), eyiti o jẹ idanimọ ni pataki (ni afikun si Gb3Cer ati Gb4Cer) nipasẹ Stx2e, jẹ ẹya ti iṣeto ni kikun.Awọn lipoforms ti awọn GSL olugba Stx ni a rii ni pataki awọn ohun elo ceramide ti o ni sphingosine (d18:1) ati C24: 0/C24: 1 tabi C16: 0 fatty acid.Pẹlupẹlu, iṣọpọ-iṣẹlẹ pẹlu awọn ami ami raft lipid, SM ati idaabobo awọ, ni awọn DRMs daba ajọṣepọ GSL pẹlu microdomains awo.Iwadi yii n pese ipilẹ fun wiwa siwaju si ipa iṣẹ ti awọn olugba Stx ti o ni nkan ṣe pẹlu raft raft fun ipalara ti majele ti awọn sẹẹli Vero-B4.

 


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    BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine iyọ Cas:6578-06-9 99% Funfun si ina brown lulú