Ninu wiwa ti o tẹsiwaju fun ailewu ati lilo oogun antidiabetic, ewe omi di orisun pataki eyiti o pese ọpọlọpọ awọn agbo ogun ti agbara itọju ailera pupọ.Alpha-amylase, alpha-glucosidase inhibitors, ati awọn agbo ogun antioxidant ni a mọ lati ṣakoso àtọgbẹ ati pe wọn ti gba akiyesi pupọ laipẹ.Ninu iwadi ti o wa lọwọlọwọ, awọn ewe alawọ ewe mẹrin (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, ati Cladophora rupestris) ni a yan lati ṣe ayẹwo awọn alpha-amylase, alpha-glucosidase inhibitory, ati iṣẹ-ṣiṣe antioxidant in vitro.Awọn eroja phytochemical ti gbogbo awọn ayokuro ni a ti pinnu ni qualitatively. .Iṣẹ ṣiṣe antidiabetic jẹ iṣiro nipasẹ agbara inhibitory ti awọn ayokuro lodi si alpha-amylase ati alpha-glucosidase nipasẹ awọn igbelewọn spectrophotometric.Iṣẹ-ṣiṣe Antioxidant ni ipinnu nipasẹ 2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), ati ayẹwo nitric oxide scavenging.Gas chromatography-mass spectrometry (GC-MS) onínọmbà ti a ti gbe jade lati mọ awọn pataki yellow lodidi fun awọn oniwe-antidiabetic igbese.Lara awọn orisirisi ayokuro ti a ti ṣayẹwo, chloroform jade ti C. aerea (IC50 - 408.9 μg/ml) ati methanol jade ti Chlorodesmis (IC50 - 147.6 μg / ml) ṣe afihan idinamọ ti o munadoko lodi si alpha-amylase.Awọn ayokuro naa tun ṣe ayẹwo fun idinamọ alpha-glucosidase, ko si si iṣẹ ṣiṣe ti a rii.Methanol jade ti C. rupestris ṣe afihan iṣẹ-ṣiṣe radical radicals ti o ṣe akiyesi (IC50 - 666.3 μg / ml), atẹle H2O2 (34%) ati nitric oxide (49%).Siwaju sii, profaili kemikali nipasẹ GC-MS ṣe afihan wiwa ti awọn agbo ogun bioactive pataki.Phenol, 2,4-bis (1,1-dimethylethyl) ati z, z-6,28-heptatriactontadien-2-ọkan ni a ti rii ni pataki ninu iyọkuro methanol ti C. rupestris ati chloroform jade ti C. aerea. Awọn abajade wa ṣe afihan pe awọn ewe ti o yan ṣe afihan idinamọ alpha-amylase ti o ṣe akiyesi ati iṣẹ-ṣiṣe antioxidant.Nitorina, ijuwe ti awọn agbo ogun ti nṣiṣe lọwọ ati awọn iṣeduro ti o wa ninu vivo yoo jẹ akiyesi.Awọn alawọ ewe mẹrin ti a yan lati ṣe ayẹwo alpha-amylase, alpha-glucosidase inhibitory, ati iṣẹ-ṣiṣe antioxidant ni vitro C. aerea ati Chlorodesmis ṣe afihan idinamọ pataki lodi si alpha-amylase, ati C. rupestris ṣe afihan iṣẹ-ṣiṣe scavenging radical ọfẹ ti o ṣe akiyesi Ko si iṣẹ ṣiṣe ti a rii lodi si itupalẹ alpha-glucosidaseGC-MS ti awọn ayokuro ti nṣiṣe lọwọ ṣafihan wiwa ti awọn agbo ogun pataki eyiti o funni ni oye lori antidiabetic ati iṣẹ antioxidant ti awọn ewe wọnyi.Awọn kukuru ti a lo: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.
