Awọn ọja

4-Chlorophenylboronic acid jẹ ohun elo Organic ti o rii ohun elo jakejado ni awọn aaye pupọ, pẹlu iṣelọpọ Organic, kemistri oogun, ati imọ-jinlẹ ohun elo.O ni oruka phenyl ti o rọpo pẹlu ẹgbẹ chloro (-Cl) ati ẹgbẹ acid boronic (-B (OH) 2) . Ọkan ninu awọn lilo akọkọ ti 4-Chlorophenylboronic acid ni ipa rẹ bi ohun ti o niyelori reagent ni palladium-catalyzed awọn aati idapọmọra, gẹgẹbi Suzuki-Miyaura ati awọn aati Heck.Awọn aati wọnyi jẹ pẹlu dida awọn ifunmọ erogba-erogba, nibiti 4-Chlorophenylboronic acid ṣe n ṣiṣẹ bi orisun boron ti o le ṣajọpọ pẹlu ọpọlọpọ awọn elekitirofu Organic, gẹgẹbi aryl tabi awọn halides fainali.Eyi jẹ ki iṣelọpọ ti awọn orisirisi agbo ogun Organic, pẹlu awọn oogun, awọn agrochemicals, ati awọn ohun elo.Ni afikun, 4-Chlorophenylboronic acid le jẹ atunṣe ti kemikali siwaju sii lati ṣafihan awọn ẹgbẹ iṣẹ-ṣiṣe afikun.Fun apẹẹrẹ, o le faragba awọn aati amination lati dagba 4-chloro-phenylboronates, eyi ti o le jẹ wulo agbedemeji fun awọn kolaginni ti awọn orisirisi agbo ogun ti o ni nitrogen.Oniruuru ẹgbẹ iṣẹ-ṣiṣe yii n mu ohun elo sintetiki ti 4-Chlorophenylboronic acid, gbigba fun ṣiṣẹda awọn ohun elo ti o nipọn pẹlu awọn ohun-ini ti a ṣe.O ti ṣe afihan ileri bi elegbogi tabi bulọọki ile fun idagbasoke awọn agbo ogun bioactive.Nitori ohun elo boronate, 4-Chlorophenylboronic acid le ṣe awọn ifunmọ covalent ti o ni iyipada pẹlu awọn ohun elo ti o ni diol, gẹgẹbi awọn carbohydrates ati awọn nucleotides.Ibaraẹnisọrọ yii ti ni agbara lati ṣe apẹrẹ awọn inhibitors enzyme, awọn ligands olugba, ati awọn aṣoju elegbogi miiran.Fun apẹẹrẹ, awọn inhibitors proteasome ti o da lori acid boronic acid ti ni idagbasoke fun itọju ọpọlọpọ myeloma.Ni aaye ti imọ-ẹrọ ohun elo, 4-Chlorophenylboronic acid ti ri ohun elo ni iyipada ti awọn ipele tabi iṣelọpọ awọn ohun elo iṣẹ.Nipa lilo ẹgbẹ acid boronic, o le ṣẹda awọn eka iparọpo to lagbara pẹlu awọn polyols tabi awọn agbo ogun ti o ni hydroxyl.Ohun-ini yii le ṣee lo fun iṣẹ ṣiṣe dada, gẹgẹbi ṣiṣẹda awọn ohun elo ti o ni idahun ti o ni idasi tabi igbaradi awọn sensọ fun wiwa awọn carbohydrates tabi awọn itupalẹ miiran.Ni akojọpọ, 4-Chlorophenylboronic acid jẹ ohun elo ti o wapọ pẹlu awọn ohun elo ti o yatọ ni iṣelọpọ Organic, kemistri oogun. , ati awọn ohun elo Imọ.Iṣe adaṣe rẹ ni didasilẹ asopọ erogba-erogba, agbara fun iṣafihan ẹgbẹ iṣẹ-ṣiṣe, ati agbara lati ṣe agbekalẹ awọn iwe ifowopamosi iyipada ti o jẹ ki o jẹ ohun elo pataki fun awọn oniwadi ni ọpọlọpọ awọn aaye imọ-jinlẹ.