4-Chloro-2-fluoro-3-methoxyphenylboronic acid CAS: 944129-07-1
Nọmba katalogi | XD93459 |
Orukọ ọja | 4-Chloro-2-fluoro-3-methoxyphenylboronic acid |
CAS | 944129-07-1 |
Fọọmu Molecularla | C7H7BClFO3 |
Òṣuwọn Molikula | 204.39 |
Awọn alaye ipamọ | Ibaramu |
Ọja Specification
Ifarahan | funfun lulú |
Asay | 99% iṣẹju |
4-Chloro-2-fluoro-3-methoxyphenylboronic acid jẹ ohun elo kemikali ti o ni orisirisi awọn ohun elo ni iṣelọpọ ti ara, kemistri oogun, ati imọ-ẹrọ ohun elo.One ti awọn lilo akọkọ ti 4-Chloro-2-fluoro-3-methoxyphenylboronic acid jẹ ni orilede irin-catalyzed agbelebu-pipade aati.O ṣe iranṣẹ bi bulọọki ile boronic acid, gbigba fun didasilẹ ti erogba-erogba tabi awọn iwe adehun carbon-heteroatom.Fún àpẹrẹ, àkópọ̀ yí le jẹ́ lò ní àwọn aati ìsopọ̀ àgbélébùú Suzuki-Miyaura, níbi tí ó ti ń fèsì pẹ̀lú aryl tàbí vinyl halides lábẹ́ palladium catalysis láti ṣe ìmújáde àwọn agbo-ogun biaryl.Awọn aati idapọmọra agbelebu wọnyi ni iṣẹ lọpọlọpọ ni iṣelọpọ ti awọn ohun elo Organic eka, pẹlu awọn ile elegbogi ati awọn agrochemicals, ati ikole awọn ohun elo Organic. The oto apapo ti chlorine, fluorine, ati methoxy awọn ẹgbẹ ninu awọn be ti 4-Chloro-2 -fluoro-3-methoxyphenylboronic acid jẹ ki iṣelọpọ ti awọn itọsẹ oniruuru pẹlu awọn ohun-ini ti a ṣe.Atọmu chlorine le ṣiṣẹ bi ẹgbẹ oludari ni awọn ilana iyipada irin-catalyzed, didari iṣesi yiyan si awọn aaye kan pato laarin moleku kan.Fidipo fluorine n pese imudara lipophilicity, eyiti o le ni agba awọn ohun-ini elegbogi ti agbo ati ilọsiwaju bioavailability rẹ.Ẹgbẹ methoxy, ni ida keji, le ṣe bi ẹgbẹ aabo tabi kopa ninu awọn iyipada kemikali orisirisi.Ninu kemistri oogun, 4-Chloro-2-fluoro-3-methoxyphenylboronic acid ati awọn itọsẹ rẹ jẹ iwulo bi awọn oludije oogun ti o pọju.Awọn ẹgbẹ iṣẹ bii chlorine ati fluorine le ṣe atunṣe awọn ibaraenisepo agbo pẹlu awọn ibi-afẹde ti ibi ati ilọsiwaju awọn ohun-ini elegbogi rẹ.Ni afikun, ẹgbẹ methoxy le jẹki iduroṣinṣin ti iṣelọpọ ti yellow ati ki o ṣe alabapin si lipophilicity ati solubility rẹ.Awọn ohun-ini wọnyi jẹ ki 4-Chloro-2-fluoro-3-methoxyphenylboronic acid jẹ aaye ibẹrẹ ti o niyelori fun idagbasoke awọn aṣoju iwosan tuntun ni awọn aaye bii oncology, awọn arun aarun, ati igbona. -3-methoxyphenylboronic acid le jẹ ki iṣelọpọ ti awọn esters boronate idurosinsin, eyiti a ti lo ninu apẹrẹ awọn ohun elo pẹlu awọn ohun-ini alailẹgbẹ.Awọn ohun elo wọnyi le ṣe afihan opitika, itanna, tabi awọn ohun-ini katalitiki, da lori akopọ ati eto wọn.Ijọpọ ti 4-Chloro-2-fluoro-3-methoxyphenylboronic acid tabi awọn itọsẹ rẹ sinu awọn ohun elo wọnyi le funni ni awọn iṣẹ-ṣiṣe pato ati mu iṣẹ wọn pọ sii. nitori kemistri to wapọ ati agbara fun ṣiṣẹda awọn ohun elo ati awọn ohun elo iṣẹ.Ipa rẹ ni iyipada irin-catalyzed awọn aati idapọmọra, ni idapo pẹlu awọn ohun-ini alailẹgbẹ ti awọn ẹgbẹ iṣẹ ṣiṣe rẹ, jẹ ki o jẹ ohun elo ti o niyelori ni iṣelọpọ Organic ati kemistri oogun.Ni afikun, erupẹ acid boronic jẹ ki dida awọn esters boronate, eyiti o ṣe alabapin si idagbasoke awọn ohun elo ilọsiwaju pẹlu awọn ohun-ini ti a ṣe.