Awọn ọja

3-tert-Butoxycarbonylphenylboronic acid, tí a tún mọ̀ sí Boc-Ph-B(OH)₂, jẹ́ èròjà apilẹ̀ àlùmọ́ọ́nì kan tí ó jẹ́ ti kíláàsì àwọn èròjà boronic.O ni oruka phenyl ti o rọpo pẹlu ẹgbẹ tert-butoxycarbonyl (Boc) ati ẹgbẹ boronic acid (-B (OH)₂).Yi yellow ni o ni kan jakejado ibiti o ti ohun elo ni Organic kolaginni, paapa ni awọn aaye ti oogun kemistri.One jc lilo ti 3-tert-Butoxycarbonylphenylboronic acid jẹ bi a Idaabobo ẹgbẹ ni Organic kolaginni.Ẹgbẹ Boc le ni yiyan ni yiyan si ẹgbẹ iṣẹ ṣiṣe amine lati daabobo rẹ lati awọn aati ti ko fẹ lakoko iṣelọpọ ti awọn ohun elo ti o nipọn.Ẹgbẹ aabo Boc jẹ iduroṣinṣin labẹ ọpọlọpọ awọn ipo ifaseyin ati pe o le yọkuro ni rọọrun nigbamii nipa lilo awọn ipo ekikan kekere, gbigba fun idabobo yiyan ti ẹgbẹ amine.Ohun-ini yii jẹ ki 3-tert-Butoxycarbonylphenylboronic acid jẹ reagent ti o niyelori ninu iṣelọpọ ti awọn peptides, awọn oogun, ati awọn ọja adayeba.Pẹlupẹlu, 3-tert-Butoxycarbonylphenylboronic acid ni a lo nigbagbogbo ni awọn aati idapọmọra, gẹgẹbi idapọpọ Suzuki-Miyaura.Ẹgbẹ boronic acid le faragba ifarahan pẹlu ẹya organometallic, ni deede aryl tabi boronate alkyl, ti o fa idasile ti mnu erogba-erogba.Iṣe yii jẹ lilo pupọ lati ṣẹda awọn ẹya molikula eka ati ṣafihan aryl tabi awọn ẹgbẹ alkyl sori moleku ibi-afẹde kan.3-tert-Butoxycarbonylphenylboronic acid, pẹlu ẹgbẹ aabo Boc rẹ, ngbanilaaye fun awọn aati idapọmọra yiyan ni awọn aaye kan pato ninu moleku kan, ti o mu ilọsiwaju sintetiki ati ṣiṣe ṣiṣẹ.Awọn acids Boronic, pẹlu awọn itọsẹ phenylboronic acid, ti ṣe afihan ọpọlọpọ awọn iṣẹ iṣe ti ibi, gẹgẹbi anticancer, antiviral, ati awọn ohun-ini antifungal.Agbara ti 3-tert-Butoxycarbonylphenylboronic acid lati kopa ninu awọn aati isọpọ-agbelebu ni a le lo lati ṣe apẹrẹ ati ṣajọpọ awọn agbo ogun aramada pẹlu awọn iṣẹ iṣe ti ibi-aye ti mu dara si.Awọn oniwadi ti ṣawari awọn iṣelọpọ ti awọn itọsẹ acid boronic ti 3-tert-Butoxycarbonylphenylboronic acid ati ki o ṣe ayẹwo agbara ti oogun wọn. Iwoye, 3-tert-Butoxycarbonylphenylboronic acid jẹ ohun elo ti o wapọ pẹlu awọn ohun elo ti o wa ninu iṣelọpọ Organic, paapaa gẹgẹbi ẹgbẹ idaabobo ati ni idapọmọra-agbelebu. awọn aati.Ẹya kẹmika alailẹgbẹ rẹ ati imuṣiṣẹsẹhin jẹ ki o jẹ reagent ti o niyelori fun iṣelọpọ ti awọn ohun elo eka, pẹlu awọn peptides ati awọn oogun.Ni afikun, awọn ohun elo itọju ailera ti 3-tert-Butoxycarbonylphenylboronic acid ati awọn itọsẹ rẹ jẹ ki o jẹ agbo ti o nifẹ fun iwadii siwaju si ni kemistri oogun.