Awọn ọja

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) jẹ ohun elo kemikali ti a mọ fun awọn ohun elo rẹ ni iṣelọpọ Organic, paapaa ni aaye ti kemistri carbohydrate.O jẹ itọsẹ ti D-glukosi, suga ti o nwaye nipa ti ara, o si ni awọn ohun-ini alailẹgbẹ ti o jẹ ki o wulo ni ọpọlọpọ awọn aati kemikali. Ọkan ninu awọn lilo akọkọ ti TMS-D-glucose lactone jẹ bi ẹgbẹ aabo ni kemistri carbohydrate.Carbohydrates, pẹlu awọn suga, le ni ọpọlọpọ awọn ẹgbẹ hydroxyl, eyiti o le fesi pẹlu awọn reagents miiran tabi faragba awọn iyipada ti aifẹ lakoko iṣelọpọ.Nipa yiyan idabobo awọn ẹgbẹ hydroxyl kan pato nipa lilo lactone TMS-D-glucose, awọn onimọ-jinlẹ le ṣakoso awọn abajade esi ati ṣe afọwọyi awọn ẹya carbohydrate ni imunadoko.Lẹhin awọn aati ti o fẹ ti pari, awọn ẹgbẹ aabo le ni irọrun kuro, ṣafihan ọja ti o fẹ.TMS-D-glucose lactone tun wa awọn ohun elo bi agbedemeji ninu iṣelọpọ ti awọn itọsẹ carbohydrate ti o nipọn diẹ sii.Nipa yiyan iyipada awọn ẹgbẹ hydroxyl ti TMS-D-glucose lactone, awọn onimọ-jinlẹ le ṣafihan ọpọlọpọ awọn ẹgbẹ iṣẹ ṣiṣe tabi awọn aropo miiran sinu moleku carbohydrate.Eyi ngbanilaaye fun ẹda ti awọn orisirisi agbo ogun ti o da lori carbohydrate pẹlu awọn ohun elo ti o ni agbara ni awọn oogun, awọn ohun ikunra, ati imọ-ẹrọ awọn ohun elo.Ni afikun, TMS-D-glucose lactone ti wa ni lilo ni iṣelọpọ ti awọn oluranlọwọ glycosyl fun awọn aati glycosylation.Glycosylation jẹ igbesẹ bọtini ni dida awọn iwe glycosidic, eyiti o ṣe pataki fun iṣelọpọ awọn carbohydrates ati glycoconjugates.TMS-D-glucose lactone le ṣe iyipada si awọn oluranlọwọ glycosyl, eyiti o ṣiṣẹ bi awọn agbedemeji ifaseyin ni awọn aati glycosylation, ti o mu ki a somọ awọn carbohydrates si awọn ohun elo miiran.Pẹlupẹlu, TMS-D-glucose lactone ti wa ni iṣẹ ni iṣelọpọ awọn polima ti o da lori carbohydrate.Nipa fifisilẹ TMS-D-glucose lactone si awọn aati polymerization, awọn onimọ-jinlẹ le ṣẹda awọn ẹwọn polima tabi awọn nẹtiwọọki pẹlu awọn eegun ẹhin carbohydrate.Awọn polima carbohydrate wọnyi le ni awọn ohun-ini alailẹgbẹ ati pe o le wa awọn ohun elo ni awọn agbegbe bii awọn eto ifijiṣẹ oogun, bioengineering, ati awọn ohun elo biomaterials.O ti wa ni deede ti o ti fipamọ ati ki o mu labẹ nitrogen tabi argon bugbamu lati dena ibaje.Ni akojọpọ, 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) jẹ ohun elo ti o wapọ ti a lo ni lilo pupọ ni kemistri carbohydrate.Awọn ohun elo akọkọ rẹ pẹlu idabobo kemistri ẹgbẹ, iṣelọpọ agbedemeji, iṣelọpọ olugbeowosile glycosyl, ati iṣelọpọ awọn polima ti o da lori carbohydrate.Nipa lilo TMS-D-glucose lactone ninu awọn ilana wọnyi, awọn onimọ-jinlẹ le ṣaṣeyọri iṣakoso to dara julọ lori awọn aati carbohydrate ati ṣẹda awọn itọsẹ carbohydrate oniruuru pẹlu awọn ohun elo ti o pọju ni awọn aaye pupọ.