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Awọn ọja

2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) - ọkan Cas: 1044871-04-6

Apejuwe kukuru:

Nọmba Katalogi: XD90961
Cas: 1044871-04-6
Fọọmu Molecular: C24H29N3O4
Ìwọ̀n Molikula: 423.5
Wiwa: O wa
Iye:  
Iṣakojọpọ:  
Apo Ọpọ: Beere Quote

 


Alaye ọja

ọja Tags

Nọmba katalogi XD90961
Orukọ ọja 2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) -ọkan

CAS

1044871-04-6

Ilana molikula

C24H29N3O4

Òṣuwọn Molikula

423.5
Awọn alaye ipamọ  
Ti irẹpọ Owo idiyele koodu  

 

Ọja Specification

Ifarahan  
Ayẹwo  
Boiling ojuami 612.6± 65.0 °C(Asọtẹlẹ)
iwuwo 1.25± 0.1 g/cm3(Asọtẹlẹ)
olùsọdipúpọ acidity (pKa) 9.54± 0.20 (Asọtẹlẹ)

 

RVX-297 jẹ alagbara ti o ga, oludanujẹ BET ti nṣiṣe lọwọ ẹnu yiyan fun BD2.Awọn IC50 ti RVX-297 fun BRD2(BD2), BRD3(BD2), ati BRD4(BD2) jẹ 0.08, 0.05, ati 0.02 μM, lẹsẹsẹ.RVX-297 ṣe idiwọ ikosile ti ọpọlọpọ awọn jiini iredodo sẹẹli ti ajẹsara.Agbara ti RVX-297 ni awọn awoṣe preclinical ti iredodo nla ati autoimmunity.


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    2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) - ọkan Cas: 1044871-04-6