Bakteria entomopathogenic kan, Xenorhabdus nematophila, nfa ajẹsara ajẹsara ti awọn kokoro ibi-afẹde nipasẹ didaduro iṣẹ-ṣiṣe phospholipase A (2) (PLA (2)).Laipe, apilẹṣẹ PLA(2) ti o niiṣe pẹlu ajesara jẹ idanimọ lati inu beetle iyẹfun pupa, Tribolium castaneum.Iwadi yii ṣe apilẹṣẹ jiini PLA (2) ninu fekito ikosile kokoro lati ṣe agbejade henensiamu atunko.T. castaneum PLA (2) (TcPLA (2)) ti o tun ṣe afihan iṣẹ-ṣiṣe enzymu abuda rẹ pẹlu ifọkansi sobusitireti, pH, ati iwọn otutu ibaramu.Awọn abuda kemikali rẹ ni ibamu pẹlu iru ikọkọ ti PLA (2) (sPLA (2)) nitori pe iṣẹ ṣiṣe rẹ ni idinamọ nipasẹ dithiothreitol (oluranlọwọ idinku ti asopọ disulfide) ati bromophenacyl bromide (olumudani sPLA (2) kan pato) ṣugbọn kii ṣe nipasẹ methylarachidonyl fluorophosphonate (iru cytosolic kan pato ti PLA (2)).Awọn broth aṣa nematophila X. ti o wa ninu PLA (2) ifosiwewe inhibitory (s), eyiti o pọ julọ ni awọn media ti o gba ni ipele idagbasoke kokoro-arun iduro.PLA(2) ifosiwewe (s) inhibitory jẹ sooro ooru ati fa jade ni awọn ida olomi ati Organic.Ipa ti PLA (2) -ida idalọwọduro lori imunosuppression ti T. castaneum jẹ afiwera bakanna pẹlu eyi ti o waye lati idinamọ ti TcPLA (2) ikosile jiini nipasẹ kikọlu RNA.
