1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas: 41575-94-4
| Nọmba katalogi | XD90684 |
| Orukọ ọja | 1,1-Cyclobutanedicarboxylatodiammine Platinum (II) |
| CAS | 41575-94-4 |
| Ilana molikula | C6H12N2O4Pt |
| Òṣuwọn Molikula | 371.25 |
| Awọn alaye ipamọ | 2-8°C |
| Ti irẹpọ Owo idiyele koodu | 28439090 |
Ọja Specification
| Ifarahan | Funfun si pa-funfun lulú |
| Ayẹwo | 99% |
| Omi | ≤0.5% |
| Isonu lori Gbigbe | ≤0.5% |
| Klorides | ≤100ppm |
| Awọn nkan ti o jọmọ | ≤0.25% |
| Eyikeyi Aisọye Aimọ | ≤ 0.1% |
| Gbogbo awọn idoti miiran | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Pilatnomu eka-iran keji awọn oogun antineoplastic.Awọn apanirun spekitiriumu ati iṣẹ antitumor jẹ iru awọn ti cisplatin, ṣugbọn solubility omi dara ju ti cisplatin lọ, ati pe majele si kidinrin tun dinku.O ni ipa itọju to dara lori akàn ẹdọfóró sẹẹli kekere, akàn ovarian, ori ati ọrun squamous cell carcinoma, tumo testicular, lymphoma buburu, bbl O tun le ṣee lo fun akàn cervical, akàn àpòòtọ, ati bẹbẹ lọ.
Awọn oogun anticancer Pilatnomu-keji ni ipilẹ awọn iṣẹ kanna ati lilo bi cisplatin.O n ṣiṣẹ diẹ sii ju cisplatin fun diẹ ninu awọn èèmọ, o si ni okun sii ju cisplatin lọ gẹgẹbi oluṣeto redio labẹ awọn ipo hypoxic.Ni akọkọ ti a lo fun akàn ovarian, akàn testicular, akàn ẹdọfóró sẹẹli kekere ati akàn ori ati ọrun.
Carboplatin jẹ oogun akàn ti o da lori Pilatnomu ti o ba DNA jẹ nipa dida iṣọpọ intrachain si awọn iyoku guanine ti o wa nitosi.Ipa antitumor ti awọn oogun wọnyi jẹ aṣeyọri nipasẹ isonu ti atunṣe aiṣedeede DNA (ajesara MMR) ati ifilọlẹ ti iku sẹẹli ti a ṣe eto.
![Rhodium, di-m-chlorobis[(1,2,5,6-h)-1,5-hexadiene] di- CAS:32965-49-4 98%](http://cdn.globalso.com/xdbiochems/32965-49-4.jpg)